Transcription profiling of Francisella tularensis mutants to identify gene required for Francisella virulence

ABSTRACT: pool 16 and pool 29 arrays represent the Francisella transposon insertion mutants isolated from the spleens of two separate groups of 5 intraperitoneally infected mice. skin arrays represent the Francisella transposon insertion mutants isolated from the skin of 5 individual, subcutaneously infected mice. input arrays represent Francisella transposon insertion mutants surviving after growth in TSB broth. Detailed Materials and Methods from Weiss et al, PNAS, 2007, In vivo negative selection screen identifies genes required for Francisella virulence: Mice and Francisella infections Female C57BL/6 mice (Jackson) between 7 and 10 wk of age were kept under specific pathogen-free conditions in filter-top cages at Stanford University and provided with sterile water and food ad libitum. Experi

ORGANISM(S): Francisella tularensis

SUBMITTER: Janos Demeter 

PROVIDER: E-SMDB-3978 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress