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Transcription profiling of amplified material from isolated ducts and islets from normal pancreas and adenocarcinomas

ABSTRACT: Isolated ducts and isolated islets from normal pancreas; normal and adenocarcinomas as labelled. The isolated ducts and islets, and three adenocarcinomas (shcx206, shcx200 and shcx 193) were amplified because of low starting amount of materials. The rest of the samples, which have previously been put on arrays unamplified, were amplified for the purpose of clustering with the isolated ducts and islets.

ORGANISM(S): Homo sapiens

SUBMITTER: Janos Demeter

PROVIDER: E-SMDB-3997 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression patterns in pancreatic tumors, cells and tissues.

Lowe Anson W AW Olsen Mari M Hao Ying Y Lee Sum P SP Taek Lee Kyu K Chen Xin X van de Rijn Matt M Brown Patrick O PO

PloS one 20070328 3

<h4>Background</h4>Cancers of the pancreas originate from both the endocrine and exocrine elements of the organ, and represent a major cause of cancer-related death. This study provides a comprehensive assessment of gene expression for pancreatic tumors, the normal pancreas, and nonneoplastic pancreatic disease.<h4>Methods/results</h4>DNA microarrays were used to assess the gene expression for surgically derived pancreatic adenocarcinomas, islet cell tumors, and mesenchymal tumors. The addition ...[more]

PMID: 17389914

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