Dataset Information
Comparative genomic hybridization of S. cerevisiae strains with selected gross chromosomal rearrangements relative to the wild-type strain
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Vincent Pennaneach
PROVIDER: E-TABM-732 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae.
PloS one 20090728 7
<h4>Background</h4>The gross chromosomal rearrangements (GCRs) observed in S. cerevisiae mutants with increased rates of accumulating GCRs include predicted dicentric GCRs such as translocations, chromosome fusions and isoduplications. These GCRs resemble the genome rearrangements found as mutations underlying inherited diseases as well as in the karyotypes of many cancers exhibiting ongoing genome instability<h4>Methodology/principal findings</h4>The structures of predicted dicentric GCRs were ...[more]
