Transcription profiling of human haematological neoplasias from blood samples and cell lines

ABSTRACT: Validation of a custom low density microarray. Gene expression differences were analysed in the following groups of blood samples and cell lines:
Two haematological neoplasia cell lines: U937 (promonocytic lymphoma) versus Jurkat (T leukemia).
Different types of haematological neoplasias: healthy donors, B-CLL patients, myeloid leukemia patients and U937 and Jurkat cell cultures samples.
Two hematological neoplasia with different origin (lymphoid for B-CLL and myeloid for the myeloid group).
Two types of myeloid leukemias (Acute myeloid leukemia and myelodisplastic syndrome).
B-CLL patients with different clinical behaviour.
Healthy donors and B-CLL patients.

Normalization was performed using two different methods, robust quantile normalization (QRN) and variance s

ORGANISM(S): Homo sapiens

DISEASE(S): B-cell chronic lymphocytic leukemia

SUBMITTER: Patricia Álvarez 

PROVIDER: E-TABM-87 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress