Body surface area-based kidney length percentiles misdiagnose small kidneys in children with overweight/obesity.

ABSTRACT: We evaluated the diagnostic performance of height-, age- and body surface area (BSA)-based kidney length (KL) percentiles in the identification of at least one small kidney (KL < 3rd) and in the prediction of reduced estimated glomerular filtration rate (eGFR) and/or elevated blood pressure (BP) in children with and without overweight (OW)/obesity(OB). In this cross-sectional study, 744 apparently healthy children (mean age 8.3 years) were recruited in a primary care setting. Clinical data were collected, and serum creatinine and KL were measured. Height-, age- and BSA-based percentiles of KL were calculated and the association of at least one small kidney per subject with reduced eGFR and/or elevated BP was explored by logistic regression. Two hundred fifty-seven out of seven hundred fort

SUBMITTER: Marzuillo P 

PROVIDER: S-EPMC10060296 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature