SARS-CoV-2 transmission among health care workers, an outbreak investigation using whole-genome sequencing.

ABSTRACT:

Background

We report an outbreak investigation to map intra-hospital transmission among health care workers (HCW) using epidemiological and whole-genome sequencing data.

Methods

Fourteen clinical wards (COVID-19 and non-COVID-19) with high infection rates of SARS-CoV-2 among HCW were selected and demographical, epidemiological and sequencing data were collected of all HCW testing positive by RT-PCR. Clustered cases were identified based on first disease onsets and differences in single nucleotide polymorphisms (SNP's) and were analysed for additional characteristics.

Results

Data was collected for 123 HCW. Out of 123 HCW, 65 (53%) worked at eight non-COVID-19 wards, 56 (46%) at four COVID-19 wards, one (<1%) worked on several wards and for one (<1%) it was unknown. On

SUBMITTER: Te Paske KS 

PROVIDER: S-EPMC10065229 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature