Impact of maternal hepatitis B carrier status on congenital abnormalities: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This study aims to explore whether maternal hepatitis B carrier status is associated with an increased risk of congenital abnormalities.

Design

A systematic review and meta-analysis of observational studies.

Data sources

PubMed, Embase (Ovid), Scopus, the China National Knowledge Infrastructure (CNKI) and the Wanfang databases.

Study selection

Five databases were searched systematically from inception to 7 September 2021. Cohort and case-control studies that investigated the association between maternal hepatitis B virus (HBV) infection and congenital abnormalities were included. This study was conducted according to MOOSE (Meta-analysis of Observational Studies in Epidemiology) guidelines.

Data extraction and synthesis

Two reviewers independe

SUBMITTER: Huang S 

PROVIDER: S-EPMC10069551 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature