Effects of 10 add-on HF-rTMS treatment sessions on alcohol use and craving among detoxified inpatients with alcohol use disorder: a randomized sham-controlled clinical trial.

ABSTRACT:

Background and aims

Alcohol use disorder (AUD) is a chronic disorder with high relapse rates. There are currently few clinical trials of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) to reduce alcohol use among AUD patients, and results are mixed. The current study tested the effect of 10 add-on sessions of HF-rTMS over the right dorsolateral pre-frontal cortex (DLPFC) on alcohol use and craving.

Design

Single-center, single blind sham-controlled parallel-group RCT (n = 80), with 3 and 6 months follow-up.

Setting

Clinical treatment center in Amsterdam, the Netherlands.

Participants

Eighty detoxified and abstinent AUD inpatients in clinical treatment (20 females, average age = 44.35 years).

Intervention

Ten sessions of active or sh

SUBMITTER: Hoven M 

PROVIDER: S-EPMC10087396 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature