Sexual disparity and the risk of second primary thyroid cancer: a paradox.

ABSTRACT:

Background

Despite extensive research on sex differences in primary thyroid cancer, there is a lack of data on the role of sex in the risk of developing second primary thyroid cancer (SPTC). We aimed to investigate the risk of SPTC development according to patient sex, with an emphasis concerning previous malignancy location as well as age.

Methods

Cancer survivors diagnosed with SPTC were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The SEER*Stat software package obtained standardized incidence ratios (SIR) and absolute excess risks of subsequent thyroid cancer development.

Results

Data for 9,730 (62.3%) females and 5,890 (37.7%) males were extracted for a total of 15,620 SPTC individuals. Asian/Pacific Islanders had the highest in

SUBMITTER: Hussein M 

PROVIDER: S-EPMC10186173 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature