Lower circulating zinc and selenium levels are associated with an increased risk of asthma: evidence from a meta-analysis.

ABSTRACT:

Objective

Previous studies evaluating the associations of circulating Zn and Se levels with asthma have produced inconsistent results. Therefore, we conducted a meta-analysis to summarize and quantitatively synthesize the evidence from observational research.

Design

Meta-analysis.

Setting

We searched PubMed, Web of Science and Scopus databases up to May 2019 for relevant available articles. Random-effects model was adopted to estimate the pooled standardized mean difference (SMD) with 95 % CI. Meta-regression analysis and 'leave-one-out' sensitivity analysis were used to assess heterogeneity.

Participants

The meta-analysis focused on general populations.

Results

A total of twenty-six studies for Zn and forty studies for Se were included in the meta-analy

SUBMITTER: Chen M 

PROVIDER: S-EPMC10200675 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature