Assessment of arterial stiffness to predict blood pressure response to renal sympathetic denervation.

ABSTRACT:

Background

Recent trials support the efficacy of renal sympathetic denervation (RDN) to reduce blood pressure (BP). Nevertheless, about one third of patients are considered non-responders to RDN. Previous retrospective analyses suggest arterial stiffness could predict BP response to RDN.

Aims

We prospectively assessed the potential of invasive pulse wave velocity (iPWV) to predict BP response to RDN. Additionally, we aimed to establish non-invasive models based on arterial stiffness to predict BP response to RDN.

Methods

 iPWV, magnetic resonance imaging-based markers of arterial stiffness and the carotid-femoral pulse wave velocity were recorded prior to RDN in patients with treatment resistant hypertension. Changes in daytime BP after 3 months were analysed accordin

SUBMITTER: Fengler K 

PROVIDER: S-EPMC10241279 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature