Atypical Functional Network Properties and Associated Dimensions of Child Psychopathology During Rest and Task Performance.

ABSTRACT:

Background

When brain networks deviate from typical development, this is thought to contribute to varying forms of psychopathology. However, research has been limited by the reliance on discrete diagnostic categories that overlook the potential for psychological comorbidity and the dimensional nature of symptoms.

Methods

This study examined the topology of functional networks in association with 4 bifactor-defined psychopathology dimensions-general psychopathology, internalizing symptoms, conduct problems, and attention-deficit/hyperactivity disorder symptoms-via the Child Behavior Checklist in a sample of 3568 children from the ABCD (Adolescent Brain Cognitive Development) Study. Local and global graph theory metrics were calculated at rest and during tasks of reward proces

SUBMITTER: Reimann GE 

PROVIDER: S-EPMC10382736 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature