Model-based reconstruction for simultaneous multi-slice T1 mapping using single-shot inversion-recovery radial FLASH.

ABSTRACT:

Purpose

To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH), and a nonlinear model-based reconstruction method.

Methods

SMS excitations are combined with a single-shot IR radial FLASH sequence for data acquisition. A previously developed single-slice calibrationless model-based reconstruction is extended to SMS, formulating the estimation of parameter maps and coil sensitivities from all slices as a single nonlinear inverse problem. Joint-sparsity constraints are further applied to the parameter maps to improve T1 precision. Validations of the proposed method are performed for a phantom and for the human brain and liver in 6 healthy adult subjects.

SUBMITTER: Wang X 

PROVIDER: S-EPMC10409492 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature