The Role of BMI in Allostatic Load and Risk of Cancer Death.

ABSTRACT:

Introduction

Obesity and proinflammatory conditions are associated with increased risks of cancer. The associations of baseline allostatic load with cancer mortality and whether this association is modified by body mass index (BMI) were examined.

Methods

A retrospective analysis was performed in March-September 2022 using National Health and Nutrition Examination Survey years 1988 through 2010 linked with the National Death Index through December 31, 2019. Fine and Gray Cox proportional hazard models were stratified by BMI status to estimate subdistribution hazard ratios of cancer death between high and low allostatic load status (adjusted for age, sociodemographics, and health factors).

Results

In fully adjusted models, high allostatic load was associated with a 23%

SUBMITTER: Andrzejak SE 

PROVIDER: S-EPMC10440242 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature