Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Sante Cohort.

ABSTRACT:

Objective

To study the relationships between artificial sweeteners, accounting for all dietary sources (total and by type of artificial sweetener) and risk of type 2 diabetes (T2D), in a large-scale prospective cohort.

Research design and methods

The analyses included 105,588 participants from the web-based NutriNet-Santé study (France, 2009-2022; mean age 42.5 ± 14.6 years, 79.2% women). Repeated 24-h dietary records, including brands and commercial names of industrial products, merged with qualitative and quantitative food additive composition data, enabled artificial sweetener intakes to be accurately assessed from all dietary sources. Associations between artificial sweeteners (total, aspartame, acesulfame potassium [K], and sucralose) and T2D were investigated using Cox

SUBMITTER: Debras C 

PROVIDER: S-EPMC10465821 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature