Catalyst- and metal-free C(sp²)-H bond selenylation of (N-hetero)-arenes using diselenides and trichloroisocyanuric acid at room temperature.

ABSTRACT: In this paper, we report an eco-friendly approach for the C(sp²)-H bond selenylation of imidazopyridines and other N-heteroarenes as well as simple arenes at ambient temperature. This new protocol consists of the reaction between (N-hetero)-arenes and the diorganyl-diselenides and trichloroisocyanuric acid (TCCA)-ethanol reagent system. In a short reaction time, the desired selenylated products were obtained regioselectively in good yields, with tolerance for a wide range of functional groups.

SUBMITTER: Neto JSS 

PROVIDER: S-EPMC10471583 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature