Increased paternal corticosterone exposure influences offspring behaviour and expression of urinary pheromones.

ABSTRACT:

Background

Studies have shown that paternal stress prior to conception can influence the innate behaviours of their offspring. The evolutionary impacts of such intergenerational effects are therefore of considerable interest. Our group previously showed in a model of daily stress that glucocorticoid treatment of adult male mouse breeders prior to conception leads to increased anxiety-related behaviours in male offspring. Here, we aimed to understand the transgenerational effects of paternal stress exposure on the social behaviour of progeny and its potential influence on reproductive success.

Results

We assessed social parameters including social reward, male attractiveness and social dominance, in the offspring (F1) and grand-offspring (F2). We report that paternal corticos

SUBMITTER: Hoffmann LB 

PROVIDER: S-EPMC10478242 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature