Narrative review: respiratory tract microbiome and never smoking lung cancer.

ABSTRACT:

Background and objective

The lung microbiome was previously thought to be a sterile environment where only gaseous exchange takes place, but recent studies have shown the presence of microbiota in the lung. This review investigates the current literature on the effects of an environmental driven dysbiosis on the healthy oral and respiratory microbiome and its relationship to lung cancer risk in never-smokers.

Methods

An online electronic search was performed on PubMed of all English-language literature using combinations of the following keywords: "lung cancer", "dysbiosis", "non-smokers", "oral microbiome", and "respiratory microbiome". All population-based studies reporting results on oral and/or respiratory microbiome in adults were considered for our narrative review.

SUBMITTER: Pindling S 

PROVIDER: S-EPMC10482636 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature