Speech characteristics yield important clues about motor function: Speech variability in individuals at clinical high-risk for psychosis.

ABSTRACT:

Background and hypothesis

Motor abnormalities are predictive of psychosis onset in individuals at clinical high risk (CHR) for psychosis and are tied to its progression. We hypothesize that these motor abnormalities also disrupt their speech production (a highly complex motor behavior) and predict CHR individuals will produce more variable speech than healthy controls, and that this variability will relate to symptom severity, motor measures, and psychosis-risk calculator risk scores.

Study design

We measure variability in speech production (variability in consonants, vowels, speech rate, and pausing/timing) in N = 58 CHR participants and N = 67 healthy controls. Three different tasks are used to elicit speech: diadochokinetic speech (rapidly-repeated syllables e.g., papapa…

SUBMITTER: Hitczenko K 

PROVIDER: S-EPMC10505148 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature