Trichoderma harzianum Peptaibols Stimulate Plant Plasma Membrane H⁺-ATPase Activity.

ABSTRACT: Because of their ability to promote growth, act as biopesticides, and improve abiotic stress tolerance, Trichoderma spp. have been used for plant seed coating. However, the mechanism for the promotion of plant growth remains unknown. In this study, we investigate the effect of fungal extracts on the plant plasma membrane (PM) H⁺-ATPase, which is essential for plant growth and often a target of plant-associated microbes. We show that Trichoderma harzianum extract increases H⁺-ATPase activity, and by fractionation and high-resolution mass spectrometry (MS), we identify the activating components trichorzin PA (tPA) II and tPA VI that belong to the class of peptaibols. Peptaibols are nonribosomal peptides that can integrate into membranes and form indiscrimi

SUBMITTER: Bjork PK 

PROVIDER: S-EPMC10536087 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature