Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites.

ABSTRACT: There is evidence that the association of protein intake and frailty may depend on the source of dietary protein. The mechanism underlying this association is not clear. In this study, we explore circulating metabolites as mediators of the relationship between dietary protein and of frailty in participants of the Baltimore Longitudinal Study of Aging (BLSA). Cross-sectional analyses in 735 BLSA participants of associations between plant and animal protein intake and frailty. Usual protein intake from plant and animal sources were estimated with a Food Frequency Questionnaire (FFQ) and frailty was assessed with a 44-item Frailty Index (FI). Compared with the lowest quartile, higher quartiles of plant, but not animal, protein were associated with lower FI. Twenty-five plasma metabolites were

SUBMITTER: Tanaka T 

PROVIDER: S-EPMC10574762 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature