Vagus Nerve Ultrasonography Helps Distinguish Multiple System Atrophy from Other Parkinsonian Syndromes.

ABSTRACT:

Background

Distinguishing multiple system atrophy from other parkinsonian syndromes is challenging.

Objectives

To evaluate vagus nerve ultrasonography for differentiating parkinsonian syndromes.

Methods

A single-center, cross-sectional, observational study assessed 85 consecutive adult patients with de novo parkinsonism between June 2020 and December 2022, using 12 MHz ultrasonography of the vagus nerve cross-sectional area.

Results

Bilateral vagus nerves were smaller in multiple system atrophy than in other parkinsonian syndromes. The area under the receiver operating characteristic curve for differentiating multiple system atrophy was 0.79 on the right side and 0.74 on the left. The cut-off values to diagnose multiple system atrophy were 0.71 and 0.86 mm

SUBMITTER: Oura K 

PROVIDER: S-EPMC10585973 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature