Probiotics as a complementary treatment in systemic lupus erythematosus: A systematic review.

ABSTRACT:

Introduction

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that primarily affects young women. SLE has no recognized etiology but it is believed to be triggered by a number of factors, including genetic predisposition, hormonal influences, and environmental conditions. Dysbiosis in the gut microbiota has emerged as a potential mechanism connecting the intestinal microbiome to the breakdown of self-tolerance and chronic inflammation. This review aims to investigate the role of probiotics in modulating the gut microbiome and their potential therapeutic benefits in managing SLE, providing insights for future research and clinical practice.

Methods

We conducted a thorough search for papers published up to June 2023 in databases such as PubMed/MEDLINE, Web of

SUBMITTER: Mirfeizi Z 

PROVIDER: S-EPMC10591540 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature