The FCGR2A Is Associated with the Presence of Atherosclerotic Plaques in the Carotid Arteries-A Case-Control Study.

ABSTRACT:

Background

Atherosclerotic plaques in carotid arteries (APCA) are a prevalent condition with severe potential complications. Studies continuously search for innovative biomarkers for APCA, including those participating in cellular metabolic processes, cell adhesion, immune response, and complement activation. This study aimed to assess the relationship between APCA presence and a broad range of cardiometabolic biomarkers in the general population.

Methods

The study group consisted of consecutive participants of the population study Bialystok PLUS. The proximity extension assay (PEA) technique from the Olink Laboratory (Uppsala, Sweden) was used to measure the levels of 92 cardiometabolic biomarkers.

Results

The study comprised 693 participants (mean age 48.78 ± 15.27

SUBMITTER: Szpakowicz A 

PROVIDER: S-EPMC10607679 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature