Experimental validation of multi-fraction online adaptations in magnetic resonance guided radiotherapy.

ABSTRACT:

Background and purpose

Radiotherapy plan verification is generally performed on the reference plan based on the pre-treatment anatomy. However, the introduction of online adaptive treatments demands a new approach, as plans are created daily on different anatomies. The aim of this study was to experimentally validate the accuracy of total doses of multi-fraction plan adaptations in magnetic resonance imaging guided radiotherapy in a phantom study, isolated from the uncertainty of deformable image registration.

Materials and methods

We experimentally verified the total dose, measured on external beam therapy 3 (EBT3) film, using a treatment with five online adapted fractions. Three series of experiments were performed, each focusing on a category of inter-fractional variation

SUBMITTER: van den Dobbelsteen M 

PROVIDER: S-EPMC10685304 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature