Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis.

ABSTRACT:

Background

Diesel exhaust (DE) is human carcinogen with sufficient evidence only for lung cancer. Systematic evidence on other cancer types is scarce, thus we aimed to systematically review current literature on the association between occupational DE exposure and risk of liver and pancreatic cancers.

Methods

We performed a systematic literature review to identify cohort studies on occupational DE exposure and risk of cancers other than lung. We computed pooled relative risks (RRs) and corresponding 95% confidence intervals (CIs) for liver and pancreatic cancers using DerSimonian and Laird random-effects model.

Results

Fifteen studies reporting results on pancreatic cancer and fourteen on liver cancer were included. We found a weakly increased risk of pancreatic cance

SUBMITTER: Sassano M 

PROVIDER: S-EPMC10995068 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature