The association between C-reactive protein and coronary artery calcification: a systematic review and meta-analysis.

ABSTRACT:

Background

While coronary artery calcification (CAC) is recognized as a reliable marker for coronary atherosclerosis, the relationship between the concentration of C-reactive protein (CRP) and the incidence and progression of CAC remains controversial.

Method

PubMed, Embase, Web of Science, and Scopus were systematically searched to identify relevant observational studies until October 2023. The methodological quality of the included studies was evaluated using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was employed to calculate pooled odd ratios (OR) and corresponding 95% confidence intervals, considering heterogeneity among the studies.

Results

Out of the 2545 records, 42 cross-sectional and 9 cohort studies were included in the systematic revi

SUBMITTER: Tajani A 

PROVIDER: S-EPMC11007925 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature