Precision Colorectal Cancer Fecal Immunological Test Screening With Fecal-Hemoglobin-Concentration-Guided Interscreening Intervals.

ABSTRACT:

Importance

Given a gradient relationship between fecal hemoglobin (f-Hb) concentration and colorectal neoplasia demonstrated previously, using f-Hb-guided interscreening interval has increasingly gained attention in population-based fecal immunological test (FIT), but it is very rare to address how to implement such a precision strategy and whether it can economize the use of FIT and colonoscopy.

Objective

To demonstrate the applicability of personalized colorectal cancer (CRC) screening with f-Hb-guided screening intervals to reduce the number of FITs and colonoscopy with as equivalent efficacy as universal biennial screening.

Design, setting, and participants

A retrospective cohort study for developing f-Hb-guided precision interscreening interval was conducted usin

SUBMITTER: Yen AM 

PROVIDER: S-EPMC11082752 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature