Recurrence in Eyelid Sebaceous Carcinoma: A Multicentric Study of 418 Patients.

ABSTRACT:

Purpose

Local recurrence predicts dismal prognosis in eyelid sebaceous carcinoma (SC). Recurrence predictors vary across studies. Accurate recurrence estimation is essential for individualized therapy in eyelid SC. This study aims to identify recurrence predictors and develop a nomogram for personalized prediction in eyelid SC.

Methods

We conducted a multicenter retrospective cohort study. Chart reviews were performed in 418 consecutive patients with eyelid SC. All patients were followed up after their initial surgery. Multivariate Cox regression was used to explore the independent predictors of recurrence. A nomogram for recurrence prediction was developed and validated with bootstrap resampling. The predictive accuracy and discriminative ability were compared with the Tumo

SUBMITTER: Xu M 

PROVIDER: S-EPMC11305426 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature