Transcriptional response of Saccharomyces cerevisiae to desiccation and rehydration.

ABSTRACT: A transcriptional analysis of the response of Saccharomyces cerevisiae strain BY4743 to controlled air-drying (desiccation) and subsequent rehydration under minimal glucose conditions was performed. Expression of genes involved in fatty acid oxidation and the glyoxylate cycle was observed to increase during drying and remained in this state during the rehydration phase. When the BY4743 expression profile for the dried sample was compared to that of a commercially prepared dry active yeast, strikingly similar expression changes were observed. The fact that these two samples, dried by different means, possessed very similar transcriptional profiles supports the hypothesis that the response to desiccation is a coordinated event independent of the particular conditions involved in water remova

SUBMITTER: Singh J 

PROVIDER: S-EPMC1317403 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature