Survey of genomic diversity among Enterococcus faecalis strains by microarray-based comparative genomic hybridization.

ABSTRACT: We have compared nine Enterococcus faecalis strains with E. faecalis V583 by comparative genomic hybridization using microarrays (CGH). The strains used in this study (the "test" strains) originated from various environments. CGH is a powerful and promising tool for obtaining novel information on genome diversity in bacteria. By CGH, one obtains clues about which genes are present or divergent in the strains, compared to a reference strain (here, V583). The information obtained by CGH is important from both ecological and systematic points of view. CGH of E. faecalis showed considerable diversity in gene content: Compared to V583, the percentage of divergent genes in the test strains varied from 15% to 23%, and 154 genes were divergent in all strains. The main variation was found in region

SUBMITTER: Aakra A 

PROVIDER: S-EPMC1855650 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature