Ontology highlight
ABSTRACT:
SUBMITTER: Remmers EF
PROVIDER: S-EPMC2923807 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Nature genetics 20100711 8
Behçet's disease is a genetically complex disease of unknown etiology characterized by recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed a genome-wide association study with 311,459 SNPs in 1,215 individuals with Behçet's disease (cases) and 1,278 healthy controls from Turkey. We confirmed the known association of Behçet's disease with HLA-B*51 and identified a second, independent association within the MHC Class I region. We also identified an associati ...[more]