Identification of common differentially expressed genes in urinary bladder cancer.

ABSTRACT:

Background

Current diagnosis and treatment of urinary bladder cancer (BC) has shown great progress with the utilization of microarrays.

Purpose

Our goal was to identify common differentially expressed (DE) genes among clinically relevant subclasses of BC using microarrays.

Methodology/principal findings

BC samples and controls, both experimental and publicly available datasets, were analyzed by whole genome microarrays. We grouped the samples according to their histology and defined the DE genes in each sample individually, as well as in each tumor group. A dual analysis strategy was followed. First, experimental samples were analyzed and conclusions were formulated; and second, experimental sets were combined with publicly available microarray datasets and were furth

SUBMITTER: Zaravinos A 

PROVIDER: S-EPMC3070717 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature