Components of cross-frequency modulation in health and disease.
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ABSTRACT:
SUBMITTER: Allen EA
PROVIDER: S-EPMC3139214 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Components of cross-frequency modulation in health and disease.
Allen Elena A EA Liu Jingyu J Kiehl Kent A KA Gelernter Joel J Pearlson Godfrey D GD Perrone-Bizzozero Nora I NI Calhoun Vince D VD
Frontiers in systems neuroscience 20110714
The cognitive deficits associated with schizophrenia are commonly believed to arise from the abnormal temporal integration of information, however a quantitative approach to assess network coordination is lacking. Here, we propose to use cross-frequency modulation (cfM), the dependence of local high-frequency activity on the phase of widespread low-frequency oscillations, as an indicator of network coordination and functional integration. In an exploratory analysis based on pre-existing data, we ...[more]
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