Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC3602454 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Sun Xiaowen X Liu Dongyuan D Zhang Xiaofeng X Li Wenbin W Liu Hui H Hong Weiguo W Jiang Chuanbei C Guan Ning N Ma Chouxian C Zeng Huaping H Xu Chunhua C Song Jun J Huang Long L Wang Chunmei C Shi Junjie J Wang Rui R Zheng Xianhu X Lu Cuiyun C Wang Xiaowu X Zheng Hongkun H
PloS one 20130319 3
Large-scale genotyping plays an important role in genetic association studies. It has provided new opportunities for gene discovery, especially when combined with high-throughput sequencing technologies. Here, we report an efficient solution for large-scale genotyping. We call it specific-locus amplified fragment sequencing (SLAF-seq). SLAF-seq technology has several distinguishing characteristics: i) deep sequencing to ensure genotyping accuracy; ii) reduced representation strategy to reduce se ...[more]