Supratentorial ependymoma: disease control, complications, and functional outcomes after irradiation.

ABSTRACT:

Purpose

Ependymoma is less commonly found in the supratentorial brain and has known clinical and molecular features that are unique. Our single-institution series provides valuable information about disease control for supratentorial ependymoma and the complications of supratentorial irradiation in children.

Methods and materials

A total of 50 children with newly diagnosed supratentorial ependymoma were treated with adjuvant radiation therapy (RT); conformal methods were used in 36 after 1996. The median age at RT was 6.5 years (range, 1-18.9 years). The entire group was characterized according to sex (girls 27), race (white 43), extent of resection (gross-total 46), and tumor grade (anaplastic 28). The conformal RT group was prospectively evaluated for neurologic, endocrine

SUBMITTER: Landau E 

PROVIDER: S-EPMC3705553 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature