Ontology highlight
ABSTRACT:
SUBMITTER: Hadiwikarta WW
PROVIDER: S-EPMC3794611 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Nucleic acids research 20130808 18
Within a single infected individual, a virus population can have a high genomic variability. In the case of HIV, several mutations can be present even in a small genomic window of 20-30 nucleotides. For diagnostics purposes, it is often needed to resequence genomic subsets where crucial mutations are known to occur. In this article, we address this issue using DNA microarrays and inputs from hybridization thermodynamics. Hybridization signals from multiple probes are analysed, including strong s ...[more]