Dosimetric consequences of interobserver variability in delineating the organs at risk in gynecologic interstitial brachytherapy.

ABSTRACT:

Purpose

To investigate the dosimetric variability associated with interobserver organ-at-risk delineation differences on computed tomography in patients undergoing gynecologic interstitial brachytherapy.

Methods and materials

The rectum, bladder, and sigmoid of 14 patients treated with gynecologic interstitial brachytherapy were retrospectively contoured by 13 physicians. Geometric variability was calculated using κ statistics, conformity index (CIgen), and coefficient of variation (CV) of volumes contoured across physicians. Dosimetric variability of the single-fraction D0.1cc and D2cc was assessed through CV across physicians, and the standard deviation of the total EQD2 (equivalent dose in 2 Gy per fraction) brachytherapy dose (SD(TOT)) was calculated.

Results

The

SUBMITTER: Damato AL 

PROVIDER: S-EPMC4180236 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature