A haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genomes.

ABSTRACT:

Background

Bread wheat is an allopolyploid species with a large, highly repetitive genome. To investigate the impact of selection on variants distributed among homoeologous wheat genomes and to build a foundation for understanding genotype-phenotype relationships, we performed population-scale re-sequencing of a diverse panel of wheat lines.

Results

A sample of 62 diverse lines was re-sequenced using the whole exome capture and genotyping-by-sequencing approaches. We describe the allele frequency, functional significance, and chromosomal distribution of 1.57 million single nucleotide polymorphisms and 161,719 small indels. Our results suggest that duplicated homoeologous genes are under purifying selection. We find contrasting patterns of variation and inter-variant associat

SUBMITTER: Jordan KW 

PROVIDER: S-EPMC4389885 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature