Functional Polymorphisms in COX-2 Gene Are Correlated with the Risk of Oral Cancer.

ABSTRACT:

Background

This meta-analysis investigated the association between functional COX-2 gene polymorphisms and the risk of oral cancer.

Methods

Several electronic databases were searched for published studies using combinations of keywords related to COX-2 gene polymorphisms and oral cancer. After selection of relevant studies, following strict inclusion and exclusion criteria, data was performed using STATA 12.0 software.

Results

We retrieved 83 studies from database search using specific search terms. After multiple rounds of selection and elimination, 7 studies were finally identified as suitable to be included in our present meta-analysis, based on their relevance and data integrity. These 7 studies contained a combined total of 2,296 oral cancer patients and 3,647 he

SUBMITTER: Li D 

PROVIDER: S-EPMC4419230 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature