Gestational weight gain and the risk of offspring obesity at 10 and 16 years: a prospective cohort study in low-income women.

ABSTRACT:

Objective

To study the association between gestational weight gain (GWG) and offspring obesity risk at ages chosen to approximate prepuberty (10 years) and postpuberty (16 years).

Design

Prospective pregnancy cohort.

Setting

Pittsburgh, PA, USA.

Sample

Low-income pregnant women (n = 514) receiving prenatal care at an obstetric residency clinic and their singleton offspring.

Methods

Gestational weight gain was classified based on maternal GWG-for-gestational-age Z-score charts and was modelled using flexible spline terms in modified multivariable Poisson regression models.

Main outcome measures

Obesity at 10 or 16 years, defined as body mass index (BMI) Z-scores ≥95th centile of the 2000 CDC references, based on measured height and weight.

Resul

SUBMITTER: Diesel JC 

PROVIDER: S-EPMC4565617 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature