Impact of Human Enterovirus 71 Genotypes in Meningoencephalitis in Iran.

ABSTRACT:

Background

Since the importance of poliovirus has diminished, as a result of its elimination in the majority of countries, non-polioviruses are emerging as causative agents of severe central nervous system (CNS) involvement. Outbreaks of enterovirus 71 (EV71)-associated CNS infections have recently been reported in Asia, Australia, and Europe.

Objectives

This is the first study on genotyping of EV71 in children with meningoencephalitis to be carried out in Iran, and it was conducted in order to obtain an improved understanding of the disease burden of this virus, particularly with regard to CNS involvement.

Patients and methods

Viral RNA was extracted from 170 cerebrospinal fluid samples obtained from children aged under 8 years with a primary diagnosis of aseptic men

SUBMITTER: Rahimi P 

PROVIDER: S-EPMC4744466 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature