"Cumulative Stress": The Effects of Maternal and Neonatal Oxidative Stress and Oxidative Stress-Inducible Genes on Programming of Atopy.
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ABSTRACT:
SUBMITTER: Manti S
PROVIDER: S-EPMC4967692 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
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"Cumulative Stress": The Effects of Maternal and Neonatal Oxidative Stress and Oxidative Stress-Inducible Genes on Programming of Atopy.
Manti Sara S Marseglia Lucia L D'Angelo Gabriella G Cuppari Caterina C Cusumano Erika E Arrigo Teresa T Gitto Eloisa E Salpietro Carmelo C
Oxidative medicine and cellular longevity 20160718
Although extensive epidemiological and laboratory studies have been performed to identify the environmental and immunological causes of atopy, genetic predisposition seems to be the biggest risk factor for allergic diseases. The onset of atopic diseases may be the result of heritable changes of gene expression, without any alteration in DNA sequences occurring in response to early environmental stimuli. Findings suggest that the establishment of a peculiar epigenetic pattern may also be generate ...[more]
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