Cognitive Decline and Its Risk Factors in Prevalent Hemodialysis Patients.

ABSTRACT:

Background

Cognitive impairment is common in patients treated with hemodialysis. The trajectory of cognitive function and risk factors for cognitive decline remain uncertain in this population.

Study design

Longitudinal cohort.

Setting & participants

314 prevalent hemodialysis patients.

Predictors

Age, sex, race, education level, hemodialysis vintage, cause of end-stage renal disease, and baseline history of cardiovascular disease.

Outcomes

Cognitive function as determined by a comprehensive neurocognitive battery, administered at baseline and yearly when possible. Individual cognitive test results were reduced into 2 domain scores using principal components analysis, representing memory and executive function, which were used as our coprimary outcomes a

SUBMITTER: Drew DA 

PROVIDER: S-EPMC5441943 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature