Childhood polybrominated diphenyl ether (PBDE) exposure and neurobehavior in children at 8 years.

ABSTRACT:

Background

Prenatal polybrominated diphenyl ether (PBDE) exposure has been associated with decrements in IQ and increased attention deficit/hyperactivity disorder related behaviors in children; however, data are limited for the role of postnatal exposures.

Objectives

We investigated the association between a series of childhood PBDE concentrations and Full-Scale Intelligence Quotient (FSIQ) and externalizing problems at 8 years.

Methods

We used data from 208 children in the Health Outcomes and Measures of the Environment (HOME) Study, a prospective pregnancy and birth cohort. Child serum PBDEs were measured at 1, 2, 3, 5, and 8 years; missing serum PBDE concentrations were estimated via multiple imputation. The Wechsler Intelligence Scales for Children-IV and the Beha

SUBMITTER: Vuong AM 

PROVIDER: S-EPMC5567986 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature