Low-Cytotoxicity Fluorescent Probes Based on Anthracene Derivatives for Hydrogen Sulfide Detection.

ABSTRACT: Owing to the role of H₂S in various biochemical processes and diseases, its accurate detection is a major research goal. Three artificial fluorescent probes based on 9-anthracenecarboxaldehyde derivatives were designed and synthesized. Their anion binding capacity was assessed by UV-Vis titration, fluorescence spectroscopy, HRMS, ¹HNMR titration, and theoretical investigations. Although the anion-binding ability of compound 1 was insignificant, two compounds 2 and 3, containing benzene rings, were highly sensitive fluorescent probes for HS^- among the various anions studied (HS^-, F^-, Cl^-, Br^-, I^-, AcO^-, H₂PO4- , SO32- , Cys, GSH, and Hcy). This may be explained

SUBMITTER: Shang X 

PROVIDER: S-EPMC6024568 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature