Is early measles vaccination associated with stronger survival benefits than later measles vaccination?

ABSTRACT:

Background

Measles vaccine (MV) may protect against non-measles mortality. We tested whether survival depended on age of measles vaccination.

Methods

Bandim Health Project follows children under 5 years of age through a Health and Demographic Surveillance System in rural Guinea-Bissau. Children aged 6-36 months with a vaccination card inspected were followed to the next visit or for a maximum of 6 months. In Cox proportional-hazards models adjusted for age and village cluster, we compared the survival of children vaccinated with MV early (< 9 months), as recommended (9-11 months) or late (> 12+ months) with the survival of measles-unvaccinated children. Among measles-vaccinated children, we modelled the effect of age at measles vaccination linearly to assess mortality change

SUBMITTER: Hansen JS 

PROVIDER: S-EPMC6081866 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature