Long-term outcomes after acute hypercapnic COPD exacerbation : First-ever episode of non-invasive ventilation.

ABSTRACT:

Background

Non-invasive ventilation (NIV) is used to treat acute hypercapnic respiratory failure (AHRF) in patients with chronic obstructive pulmonary disease (COPD); however, long-term outcomes following discharge are largely unknown. This study aimed to characterize long-term outcomes and identify associated markers in patients with COPD after surviving the first episode of HRF requiring NIV.

Methods

This study retrospectively analyzed 122 patients, mean age 62 ± 8 years, 52% female and forced expiratory volume in 1 s (FEV1) predicted 30 ± 13%, admitted with an acute hypercapnic exacerbation of COPD and receiving a first-ever NIV treatment between 2000 and 2012.

Results

A total of 40% of the patients required hospital readmission due to respiratory reasons within 1 

SUBMITTER: Fazekas AS 

PROVIDER: S-EPMC6209011 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature