PRELIMINARY RESULTS FROM THE SYNERGIC TRIAL: A MULTIMODAL INTERVENTION FOR MILD COGNITIVE IMPAIRMENT

ABSTRACT: Abstract Mild Cognitive Impairment (MCI) is a prevalent pre-dementia state. Emerging evidence supports that physical exercise and computerized cognitive training can independently improve cognitive outcomes. Recently, vitamin D deficiency has been associated with increased risk of progression to dementia. To date, a multimodal intervention based on physical exercises, combined with computerized cognitive training and vitamin D supplementation has not yet been tested in MCI. The SYNERGIC Trial (SYNchronizing Exercises, Remedies in Gait and Cognition) is a multisite clinical-trial aimed to improve cognition and delay progression from MCI to dementia, using the aforementioned multimodal intervention. 200 participants with MCI are being assigned to active or sham interventions. Active interven

SUBMITTER: Montero Odasso M 

PROVIDER: S-EPMC6227110 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature