Cross-sectional associations between urinary triclosan and serum thyroid function biomarker concentrations in women.

ABSTRACT:

Introduction

Exposure to the antimicrobial agent triclosan is ubiquitous. Research in animals shows that triclosan can cause decreases in thyroxine concentrations. However, the potential effects of triclosan on thyroid function in humans are unclear.

Objective

To estimate the association between urinary triclosan concentrations and serum thyroid function biomarkers in women seeking assisted reproduction treatment in the Environment and Reproductive Health (EARTH) Study.

Methods

We conducted a cross-sectional study of 317 women enrolled in the EARTH Study, a prospective preconception cohort that recruits Boston area couples. Using samples collected at study entry, we quantified urinary triclosan and serum thyroid function biomarker concentrations, specifically free and

SUBMITTER: Skarha J 

PROVIDER: S-EPMC6317095 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature